2 Minute Medicine
2 Minute Medicine® was established in 2012 by Dr. Marc D. Succi, a physician affiliated with Harvard Medical School and Massachusetts General Hospital. The aim was to address the need for reliable curation and precise reporting within the medical literature landscape. Each report from 2 Minute Medicine is authored and peer-reviewed by a medical professional. Initially, the focus was on creating brief, curated summaries of studies to help doctors stay informed about new medical findings. However, the organization quickly expanded its reach globally, recognizing a widespread demand for objective, high-quality, and concise medical reporting beyond just Harvard. At the core of our content is a unique tiered reporting system. Summaries are neatly organized in a format we call the “2 Minute Rundown,” similar to what one might share with colleagues in a hospital setting. We prioritize high-quality evidence, selecting information from systematic reviews, meta-analyses, randomized trials, and a select few high-quality observational studies. For those wanting more detail, our In-Depth sections provide comprehensive insights.
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Global
#861941
United States
#452577
Health/Medicine
#3005
Articles
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2 weeks ago |
2minutemedicine.com | Neel Mistry
1. Median overall survival was 3.1 months greater in the nivolumab plus ipilimumab group. 2. Grade 3-4 treatment-related adverse events were similar between both groups. Evidence Rating Level: 1 (Excellent)Study Rundown: Patients with unresectable hepatocellular carcinoma (HCC) face a poor prognosis, and current treatments offer limited long-term benefits. There is a need for more effective first-line therapies in this population.
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2 weeks ago |
2minutemedicine.com | Neel Mistry
1. Shoulder dystocia was less common in the early induction group compared to standard care. 2. Serious adverse events were comparable between the two groups. Evidence Rating Level: 1 (Excellent)Study Rundown: Shoulder dystocia is a serious childbirth complication that may be more likely in large for gestational age (LGA) infants. Although early delivery could potentially lower birthweight and reduce complications, it may also introduce other risks.
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2 weeks ago |
2minutemedicine.com | Neel Mistry
1. FDC obicetrapib plus ezetimibe significantly decreased LDL cholesterol levels by 48.6% compared to placebo. 2. Serious adverse events were comparable in FDC, obicetrapib, ezetimibe, and placebo groups. Evidence Rating Level: 1 (Excellent)Study Rundown: Lowering LDL cholesterol is a proven strategy to prevent atherosclerotic cardiovascular disease (ASCVD). While current therapies help, many patients remain above target LDL levels or cannot tolerate statins.
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1 month ago |
2minutemedicine.com | Neel Mistry
1. Maximum walking distance at 52 weeks was significantly improved with semaglutide. 2. There were fewer treatment-related serious adverse events in the semaglutide group compared to placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Peripheral artery disease (PAD) is a serious condition affecting circulation in the legs and is common among individuals with type 2 diabetes. Few therapies are available to improve walking and quality of life for these patients.
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1 month ago |
2minutemedicine.com | Neel Mistry
1. Gepotidacin was non-inferior to ceftriaxone plus azithromycin for the primary outcome of microbiological success. 2. There were no serious or treatment-related adverse events in either group. Evidence Rating Level: 1 (Excellent) Study Rundown: Gepotidacin is a new antibacterial agent that may be effective in treating uncomplicated urinary tract infections. Given concerns over antibiotic resistance, alternative treatments for gonorrhea are needed.
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