Drug Topics

Drug Topics is a unique news magazine that covers every aspect of pharmacy for community, independent, retail, and hospital pharmacists. Its main aim is to keep busy pharmacists updated and ready for the latest clinical, professional, business, legal, and governmental changes that impact their practices, all presented in a straightforward and digestible format. Besides offering valuable clinical insights for health-system pharmacists and those in both hospital and community environments, Drug Topics also provides essential business, financial, and regulatory guidance tailored for community pharmacists, whether they operate independently or as part of a chain.

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Tirzepatide Shows Superior Weight Loss Over Semaglutide in Phase 3 Trial

2 days ago | drugtopics.com | Ashley Gallagher

Full results from the SURMOUNT-5 (NCT05822830) phase 3 trial show that tirzepatide (Zepbound) demonstrated superiority compared to semaglutide (Wegovy) across the primary end point and 5 key secondary end points.
How Pharmacists Are Becoming More Connected as Providers Through Interoperability | NCPDP 2025

2 days ago | drugtopics.com | Brian Nowosielski |Larry King

With the help of well-established pharmacy interoperability with other health care entities, pharmacists are able to utilize data more sufficiently, connect with patients and other providers more easily, and standout amongst other health care professionals. Larry King, PharmD, Director of Product Safety & Performance at Surescripts, hosted a session at the National Council for Prescription Drug Programs (NCPDP) 2025 Annual Conference, held May 5 to May 7 in Scottsdale, Arizona.
President Trump Signs Executive Order Significantly Decreasing US Drug Prices

2 days ago | drugtopics.com | Brian Nowosielski

President Donald Trump signed an executive order Monday forcing drug manufacturers to lower their costs and make drug prices similar to the country with the lowest costs in the world, according to a White House news release.1 Serving as a wide-reaching provision that will impact millions of patients and providers around the world, President Trump claims that the order will slash drug prices in the US by 30%-80%.2 “I will be signing one of the most consequential Executive Orders in our...
Lifestyle Factors Contribute to Risk of Diabetic Nephropathy

2 days ago | drugtopics.com | Ashley Gallagher

Unhealthy eating and inadequate or excessive sleeping duration could contribute to developing diabetic nephropathy, according to results of a study published in the Journal of Diabetes Investigation. However, investigators did not find a significant association between diabetic nephropathy and smoking or drinking.1Diabetic nephropathy is the leading cause of end-stage renal failure in the United States, according to StatPearls.
Pharmacists Best-Positioned to Address Social Determinants of Health | NCPDP 2025

5 days ago | drugtopics.com | Brian Nowosielski |Vin Gupta

Pharmacists are significantly rooted in their respective communities more so than most other providers, making them the health care professionals best-positioned to address social determinants of health (SDOH). “Pharmacists are about as embedded a clinician in somebody’s community as anybody, more so probably than physicians, than nurses. They are truly the front line,” said Vin Gupta, MD, former Chief Medical Officer at Amazon Pharmacy and renowned US medical analyst.
Temtokibart Shows Efficacy in Treatment of Atopic Dermatitis

5 days ago | drugtopics.com | Killian Meara

Positive topline results have been announced from a phase 2b trial evaluating the efficacy and safety of temtokibart for the treatment of moderate to severe atopic dermatitis in adult patients, LEO Pharma announced in a release.1 The company said it is currently collecting and evaluating the full data set from the study and plans to present it at a later date.
Q&A: What AI Is, How It’s Helping Pharmacies with Compliance | NCPDP 2025

5 days ago | drugtopics.com | Brian Nowosielski |Stanley Campbell |Yi Deng

As artificial intelligence (AI) within health care is developed further, pharmacies are increasingly reaping its benefits and are now using AI data to stay compliant with federal and state government regulations. “With AI, we're actually doing about 3 and a half billion calculations in about 50 milliseconds and giving a response into the [pharmacist’s] workflow,” said Stanley V. Campbell, Jr, CEO of EagleForce Associates.
Roflumilast Foam Improves Symptoms of Scalp, Body Psoriasis

6 days ago | drugtopics.com | Killian Meara

Roflumilast foam (Zoryve) 0.3% improved signs and symptoms of psoriasis on the scalp and body in patients 12 years of age and older, according to data published in the journal JAMA Dermatology.1 The therapy is currently under FDA review and has a Prescription Drug User Fee Act (PDUFA) action date of May 22, 2025.
ACE Inhibitors Show Lower Risk of MACE for Older Patients With Type 2 Diabetes

6 days ago | drugtopics.com | Ashley Gallagher

For older patients with type 2 diabetes (T2D), initiating treatment with angiotensin-converting enzyme inhibitors (ACEIs) was associated with a trend toward lower risk of major adverse cardiac events (MACE) compared with angiotensin II receptor blockers (ARBs), according to results of a study published in Cardiovascular Diabetology.1 Diabetes is a known risk factor for cardiovascular disease, and those with diabetes have a higher risk of developing and dying from diseases such as myocardial...
Rite Aid’s Closure is a Call to Action to Address Pharmacy Payment Model

6 days ago | drugtopics.com | Killian Meara |B. Douglas Hoey

Rite Aid, which was once one of the largest pharmacy chains in the United States, recently announced it has filed its second Chapter 11 bankruptcy and will be closing all of its stores or selling them.1 The company, which has continued to face financial hardships since filing for its first Chapter 11 bankruptcy in 2023, said its stores will remain open for the next few months so that patients can continue to receive care.