Fertility and Sterility

Fertility and Sterility® is a global journal aimed at obstetricians, gynecologists, reproductive endocrinologists, urologists, and researchers focused on infertility and human reproductive issues. It features peer-reviewed original research articles that cover clinical and laboratory studies in areas such as reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. The journal is dedicated to fostering significant research in both basic and clinical settings while also enhancing professional education in reproductive medicine.

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Articles

Assessment of folliculogenesis in ovarian tissue from young patients with Turner syndrome using a murine xenograft model

Apr 12, 2023 | fertstert.org | Ronald Peek |Sapthami Nadesapillai |Sarah Vassart |Dominique Smeets

1 Department of Obstetrics and Gynecology, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, the Netherlands 2 Gynecology Research Unit, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Av. Mounier 52, 1200 Brussels, Belgium 3 Department of Human Genetics, Radboud University Medical Center, PO Box 9101, 6500 HB Nijmegen, the Netherlands 4 Cliniques Universitaires Saint-Luc, Av. Hippocrate 10, 1200 Brussels, Belgium 5 Amalia Children’s...
The last frontier of reproductive medicine

Apr 8, 2023 | fertstert.org | Dominique de Ziegler |Hôpital Foch |Jean Marc Ayoubi

Fresh versus frozen embryo transfer: New approach to minimize the limitations of using national surveillance data for clinical research
Pros and Cons of Mendelian Randomization

Mar 27, 2023 | fertstert.org | Heping Zhang

Précis: Randomization in a randomized controlled trial is a critical and effect step that is designed for us to evaluate the casual effect of specific interventions on certain outcomes. Mendelian randomization is a method based on the observation that an offspring inherits genetic materials half and half randomly from each of her or his parents.
More Is Better: Oocyte Number and Cumulative Live Birth Rate

Mar 24, 2023 | fertstert.org | Helen Kim

To investigate the association between the number of oocytes retrieved and fertilized oocytes, blastocysts, cumulative live birth rate, and primary transfer live birth rate.
Neither relevant, nor randomised: the use of ‘per embryo transferred’ in the analysis of PGT-A trials

Mar 19, 2023 | fertstert.org | Jack Wilkinson
Neither relevant, nor randomised: the use of ‘per embryo transferred’ in the analysis of PGT-A trials

Mar 19, 2023 | fertstert.org | Jack Wilkinson

RCTs may provide excellent evidence about the effectiveness of infertility interventions, but only if they are designed and analysed appropriately. We describe a common statistical error in the analysis of ART trials: use of a post-randomisation denominator. We use the example of PGT-A to illustrate how use of this inappropriate analysis can undermine the relevance of the result and nullify the benefits of random allocation.
When to pool data in a meta-analysis (and when not to)?

Mar 19, 2023 | fertstert.org | Sarah Lensen

Instead of conducting meta-analysis as a default, our approach should be to thoughtfully consider whether meta-analysis is appropriate: are the studies sufficiently similar in their design and conduct, are they free from serious risk of bias, and has consideration been given to any observed statistical heterogeneity.
What’s Up (or Down) With Lipids in Menopause?

Mar 17, 2023 | fertstert.org | Nanette Santoro

Menopause transition adversely affected lipids and change patterns of each lipid around the menopause were different. BMI and menopause age can affect the lipid changes around the menopause.
ENDOMETRIAL RECEPTIVITY IN ADENOMYOSIS AND/OR ENDOMETRIOSIS

Mar 10, 2023 | fertstert.org | Paul Pirtea |Dominique de Ziegler |Jean Marc Ayoubi

A narrative review on endometrial receptivity in adenomyosis and/or endometriosis reveals that this parameter is difficult to assess in natural conception, as both disorders alter natural fertility. Recent data emanating from ART have allowed to study endometrial receptivity in women affected by adenomyosis and endometriosis. This has upended our views on the effects of these two disorders on embryo implantation. Today, the very existence of altered receptivity in ART is questioned.
Diminished Ovarian Reserve: Risk for Preeclampsia in IVF pregnancies

Mar 7, 2023 | fertstert.org | Pardis Hosseinzadeh |Robert A. Wild |Karl R Hansen

Corresponding Author: Karl R. Hansen, MD, PhD, Department of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd., AAT 2400, Oklahoma City, OK 73104, Phone: (405) 271-8787, Fax: (405) 271-8547. Department of Obstetrics and Gynecology, University of Oklahoma College of Medicine, Oklahoma City, OK 73104 Search for articles by this author