Gavi, the Vaccine Alliance

GAVI, known as Gavi, the Vaccine Alliance, is a global health partnership that combines efforts from both public and private sectors. Its main aim is to improve access to vaccines in low-income countries. In 2016, Gavi was responsible for over half of the total funding provided by donors for health initiatives, and it played a significant role in funding immunization efforts.

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Going door to door to beat diphtheria in Nigeria

1 week ago | gavi.org | Ekpali Saint

On a hot Saturday afternoon in May, Maryam Umar left her small drug store in Bosso Low-Cost, a locality in Nigeria’s Niger state, and headed out into the community. “Visiting [homes] to create awareness of diphtheria disease and to vaccinate children is part of my duty,” she explained. Umar pushed open a small red gate and was greeted by familiar faces. “They are children I have administered vaccines to,” she said.
Mind matters: the surprising link between mood and vaccine response

1 week ago | gavi.org | Linda Geddes

A sunny disposition could do more than lift your spirits – it could also boost your immune response to vaccines. Scientists have discovered that people who were in a more positive frame of mind when they received a COVID-19 vaccine produced more protective antibodies in response to it. The research adds to growing evidence of a link between the mind and immune system and could eventually lead to interventions that could bolster people’s response to vaccination.
Eight things you need to know about the new “Nimbus” and “Stratus” COVID-19 variants

1 week ago | gavi.org | Linda Geddes

COVID-19 may have faded from news headlines, but it hasn’t gone away – or stopped evolving. The World Health Organization (WHO) currently lists six ‘variants under monitoring’ -- meaning they may require prioritised attention and tracking by health authorities due to their increased prevalence and potential public health implications.
How Rwanda is beating back hepatitis B

1 week ago | gavi.org | Hudson Kuteesa

Two years ago, Clementine*, 32, visited the University Teaching Hospital of Kigali (CHUK). She was two-and-a-half months pregnant, and hadn’t planned to visit the health facility so soon. However, her husband had been recently diagnosed with hepatitis B, and she was concerned. “I was feeling fine and had no symptoms, but when they tested me, I turned out to be positive. They checked my viral load and found it was very low, so I didn’t need to start medication at that time,” she recalls.
Uncovering the Exposome: An Emerging Field Casts a Wide Net

1 week ago | gavi.org | Emma Foehringer Merchant

The lab buildings of Long Island’s renowned Cold Spring Harbor Laboratory have hosted researchers responsible for some of the most consequential scientific leaps in human genetics and disease. In the last 60 years, eight of the lab’s scientists have earned Nobel Prizes, including for work on how viruses replicate, on chromosome structure, and how edited genes can cause disease.
Measles and pregnancy: 5 things doctors urgently want you to know

2 weeks ago | gavi.org | Linda Geddes

Doctors working directly with measles outbreaks in Canada have released a paper summarising the key information that pregnant people and their doctors should know about the disease and how to stay safe. Their intervention comes as the country grapples with its first death from measles this year – the infant having contracted it before birth from their mother, who hadn’t been vaccinated against the disease.
Book Review: The Precarious Dance of Humans and Microbes

2 weeks ago | gavi.org | Lina Zeldovich

In 1676, Dutch fabric merchant Antonie van Leeuwenhoek held a magnifying glass to a sample of rainwater and saw a slew of tiny creatures squirming around. The first to observe such microscopic beings, he named them animalcules, later finding them in freshwater, seawater, and well water. As he watched them in action, he made detailed drawings and descriptions of their movements.
No more second shots: a step towards self-boosting vaccines

3 weeks ago | gavi.org | Linda Geddes

Immunisation is one of the most effective public health interventions going. Yet, around the world, millions of children are not fully immunised, putting them at risk of preventable disability and death. One issue is that many vaccines require more than one dose to be fully effective, and many children around the world receive one dose in the recommended vaccination schedule, however various logistical, economic, educational and cultural challenges mean that they don’t receive the remaining doses.
Cholera-hit Ghana guns for improved surveillance, infrastructure

3 weeks ago | gavi.org | Francis Kokutse

On 20 January this year, a day she remembers well, Naa Nyerley Otoo rushed her two children to Korle Bu Polyclinic in Accra, thinking she was about to lose them. “We were all going to toilet, and initially, I thought we had eaten something bad. It was when we got to the clinic that they said we had cholera”. Similar cases were cropping up up across the country.
Vomit-proof: how close are we to a norovirus vaccine?

3 weeks ago | gavi.org | Linda Geddes

In a new study, researchers have shown that an experimental oral vaccine triggers antibodies that can neutralise a wide range of norovirus strains. It may also reduce the amount of virus that infected people shed, raising hopes that a broadly protective vaccine may be within reach. Norovirus cases this winter have surged to twice the two previous annual peaks, which really underscores the fact that norovirus is both prevalent and rapidly evolving. - Dr Juyeon Park, University of Texas, Austin, USA.