Pharmaceutical Microbiology Resources

Pharmaceutical Microbiology offers access to numerous free technical papers covering a wide range of topics in microbiology, pharmaceutical manufacturing, and quality control. The collection is refreshed frequently. Some of these papers are authored by Tim Sandle, while others have been contributed by visitors to the site.

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Articles

Pharmaceutical Water and Its Critical Role in Biopharmaceutical Manufacturing

3 weeks ago | pharmamicroresources.com | Tim Sandle

Pharmaceutical water is a vital component in biopharmaceutical manufacturing, playing a critical role in various processes, from drug formulation to cleaning and sterilization. Water quality directly impacts the safety, efficacy, and consistency of pharmaceutical products. The stringent regulatory standards set by agencies such as the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and the World Health Organization (WHO) underscore the importance of maintaining high purity levels.
How to Ensure an ISO Certificate Is Authentic and Valid?

3 weeks ago | pharmamicroresources.com | Tim Sandle

ISO certification is a big deal for businesses. It shows that they meet international standards for quality, safety, and efficiency. But what if the certificate is fake? Yes, that happens more often than you’d think! So the question is how do you ensure an ISO certificate is authentic and valid? Let’s simplify this in simple terms. By Emily Andersen Why Verify an ISO Certificate? Think about it. Would you trust a doctor with a fake degree? No right? The same logic applies to businesses.
Treating anthrax beyond the 'point of no return'

3 weeks ago | pharmamicroresources.com | Tim Sandle

Source: CDC - This media comes from the Centers for Disease Control and Prevention's Public Health Image Library (PHIL), with identification number #2226Anthrax, an infectious disease caused by the bacterium Bacillus anthracis, is often treatable in its early stages. But once the disease has progressed beyond the "point of no return" after just a few days, patients are most likely to die.
Will ethanol be banned in Europe as the active ingredient for hand disinfectants?

1 month ago | pharmamicroresources.com | Tim Sandle

Image by Tim SandleWith ethanol be banned in the EU as the basis for hand disinfection? Do epidemiological studies confirm an increased risk for cancer from ethanol in exposed individuals? Why is the EU considering this move now?
Microbiome new study: Human ancestral co-evolution

1 month ago | pharmamicroresources.com | Tim Sandle

Meta-organism entangled metabolic pathway of microbial 3M3SH malodor biotransformation steered by human precursor thiol conjugate substrate inABCC11 haplotypes. Scientific Reports (Sci Rep)ISSN2045-2322(online)A new microbiome study of interest. The project concerns the evolutionary roots of human ancestral ethnic group global regionalizations, as involving skin niche microbial communities.
Pharmaceutical Microbiology

1 month ago | pharmamicroresources.com | Tim Sandle

Attention pharma QC enthusiasts! Welcome to our On-Demand Pharma Microbial QC Webinar Hub, a dedicated resource center featuring a carefully curated collection of pharma webinars, all located in one place. Stay updated on latest industry developments, regulatory updates, and gain access to expert insights at your convenience. Explore our On-Demand Microbiology Webinars for valuable regulatory insights and best practices in the field.
New 3D imaging approach reveals intricate steps of virus assembly

1 month ago | pharmamicroresources.com | Tim Sandle

Left: A 2D CryoSXT projection of an HSV-1 evelopment event. Right: A 3D rendering of the budding assembly stage captured by CLXT. Image credit: Dr Kamal Nahas (CC BY 4.0)This as a fundamental study that comprehensively examines the roles of nine structural proteins in herpes simplex virus 1 (HSV-1) viral assembly. They say the thoroughly executed research yields compelling data that explain previously unknown functions of HSV-1 structural proteins.
GMP Validation - a book to guide you through the international requirements

Jan 18, 2025 | pharmamicroresources.com | Tim Sandle

Within the pharmaceutical and healthcare sector, validation and qualification form an important part of the quality system. However, understanding the differences between different regulatory agencies and the recommendations of different standards can be a bewildering project. This book seeks to provide a map and a compass for navigating the choppy waters of international regulations.
Ch-ch-ch-ch-changes: Bacteria, mutations & lab testing

Jan 11, 2025 | pharmamicroresources.com | Tim Sandle

Determining the presence of bacteria – either to know some cells are present or to target a specific number – requires growth and growth using a culture-based method is expressed by an increase in cells and/or biomass. The basis of many techniques is taking extremely low levels of various microbial types in a sample, and with the provision of suitable nutrients, atmosphere and temperature, enabling these cells to multiply up to levels that are high enough to count or identify.
The Science of Electricity and How Is It Used in a Lab Setting

Jul 14, 2023 | pharmamicroresources.com | Tim Sandle