Relias Media

3 weeks ago | reliasmedia.com | William Elliott |James Chan

By William Elliott, MD, FACP, and James Chan, PharmD, PhDThe U.S. Food and Drug Administration (FDA) has approved gepotidacin, a first-in-class antibacterial medication for the treatment of uncomplicated urinary tract infections (uUTIs). Gepotidacin is an oral triazaacenaphthylene antibiotic that inhibits two essential enzymes in bacterial deoxyribonucleic acid (DNA) replication. It will be distributed by GlaxoSmithKline as Blujepa.

Feb 14, 2025 | reliasmedia.com | Philip R. Fischer

By Philip R. Fischer, MD, DTM&HSynopsis: Some patients with acute uncomplicated appendicitis do well with initial antibiotic treatment and do not require surgical appendectomy. However, as with adults, approximately one-third of antibiotic-treated children eventually will require surgical removal of the appendix despite the initial short-term success of medical management. Source: St Peter SD, Noel-MacDonnell JR, Hall NJ, et al.

Jan 15, 2025 | reliasmedia.com | Rebecca Allen

By Rebecca H. Allen, MD, MPH, EditorSynopsis: In this randomized controlled trial, the use of transcutaneous electric nerve stimulation during endometrial biopsy did not clinically significantly reduce pain compared to placebo (median [interquartile range], 50 mm [20 mm to 80 mm] vs. 60 mm [40 mm to 100 mm]; P = 0.039), but was associated with increased satisfaction with the procedure. Source: Wu J, Lim S, Scott A, et al.

Jan 6, 2025 | reliasmedia.com | Melinda Young

By Melinda YoungEXECUTIVE SUMMARYMaternal mortality review committees (MMRCs) are facing changes that could affect how maternal deaths are investigated and reported. This could lead to fewer initiatives to lower maternal mortality and morbidity rates and also mask could increases in abortion-ban states. Georgia dismissed all members of its MMRC after ProPublica published articles about two Georgian women who died because of the state’s abortion ban.

Nov 20, 2024 | reliasmedia.com | Philip R. Fischer

By Philip R. Fischer, MD, DTM&H SYNOPSIS: Acute infectious conjunctivitis, commonly referred to as pink eye, is common in children and is caused by bacteria more often than by viruses. Nonetheless, neither the clinical course of uncomplicated cases nor the spread of infection to peers is significantly altered by treatment with topical antibiotics or by exclusion of infected children from daycare and school settings. SOURCE: Frost HM, Jenkins TC, Meece JC, et al.