The Daily Upside

5 days ago | thedailyupside.com | Sean Craig

Could the world’s best-selling drug have competition on the way? American pharmaceutical giant Bristol Myers Squibb agreed Monday to pay up to $11.1 billion to partner with Germany’s BioNTech and co-develop its next-generation immunotherapy for cancer, which could compete directly with Merck & Co.’s breakthrough treatment Keytruda. At the heart of the deal is a relatively new drug technology called PD-1/VEGF bispecific antibodies. Basically, they work in two ways.

5 days ago | thedailyupside.com | Brian Boyle

While we can’t say there’s ever a bad time for a two-week summer sojourn to Palermo, there certainly have been better times than now. That’s because the US dollar is on a downward slide to its lowest point in roughly three years. While not necessarily a bad thing (unless you’re looking for cheap arancini and bottles of the house cabernet sauvignon), the dip comes just as a couple of other key US economic indicators have begun blinking red, too.

6 days ago | thedailyupside.com | Ray Fernández

As people ditch search engines as their go-to query tool in favor of AI, businesses may be forced to adapt. New data from SOCi shows that search impressions are already down 10% year-over-year across thousands of multi-location businesses, and the decline is only accelerating. The shift is poised to disrupt how people interact with brands, pressuring businesses to change their strategies for reaching customers, experts told CIO Upside.

6 days ago | thedailyupside.com | Crystal Kim

Everything is not so “gucci” in the world of luxury goods. Brands that cater to the uber-wealthy, including LVMH’s Christian Dior, Kering’s Gucci, and Chanel, saw a dip in sales for the first quarter of 2025, continuing a slowdown that started last year. While CEOs of luxury goods retailers are chalking up the challenging environment to macroeconomic turbulence, market analysis suggests the industry’s excesses of the past few years could be contributing to weakness.

6 days ago | thedailyupside.com | Brian Boyle

Here’s one delay the tourism industry is actually happy to see. Last week, shares of cruise companies and travel-booking firms surged after the White House announced it would delay its (possibly illegal) 50% tariffs on the European Union until at least July 9, allowing time for the two sides to reach a deal. Could it be the epicenter of a spring travel bug outbreak that the US tourism industry sorely needs?