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2 months ago | 
nature.com | Jacob J. Orme |Robert McWilliams |Robert Mcwilliams |Matthew Block |Aaron Mansfield |Svetomir N. Markovic | +3 more
AbstractImmune checkpoint inhibitors (ICI) are effective for advanced melanoma. However, most develop ICI resistance. Tumor-derived soluble PD-L1 (sPD-L1) and other immunosuppressive factors drive resistance. We hypothesized that therapeutic plasma exchange (TPE) may remove sPD-L1 from circulation and overcome ICI resistance. Patients with metastatic ICI-resistant melanoma and elevated sPD-L1 received radiotherapy to a minority of metastatic lesions, TPE, and ICI re-challenge.
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2 months ago | 
complex.com | Trey Alston |Aaron Mansfield |Mark Elibert
Ahead of their hyped up boxing match, KSI hit Dillon Danis in the face at a press conference — not with his fist, but with….a pancake. TMZ reports that the duo met at a press conference in London to hype up their highly anticipated match that’s set to take place on March 29. As usual with these types of events, KSI and Danis trash talked each other and went face-to-face.
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2 months ago | 
complex.com | Mark Elibert |Trey Alston |Aaron Mansfield |Joe Price
Baltimore Ravens General Manager Eric DeCosta has called the sexual misconduct allegations made against team kicker Justin Tucker "serious and concerning."During a press conference at the NFL Scouting Combine on Tuesday, DeCosta reflected on the allegations that Tucker was hit with last month.
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2 months ago | 
complex.com | Aaron Mansfield
The Eagles are Super Bowl champs, the Titans are on the clock, and the 2025 NFL Draft is loaded with stars. From Shedeur Sanders to Travis Hunter, here’s how the first round could shake out. January 1, 1970Following the Eagles’ dominant victory in Super Bowl LIX, the 2024 NFL season has officially wrapped—and that means Draft Season is upon us. When it comes to building an NFL contender, it all begins with the draft.
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2 months ago | 
complex.com | Mark Elibert |Victor Deng |Aaron Mansfield
Anthony Edwards' raw confidence was enough to surprise former President Barack Obama in the new Netflix docuseries Court of Gold that debuted on Tuesday. In the show, which follows various NBA players playing in the 2024 Paris Summer Olympics, Team USA got the chance to catch up with Obama, and one of the interactions shows just how much Edwards believes in himself.
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Jan 14, 2025 | 
yahoo.com | Aaron Mansfield
Despite all the complaints about the state of the league this season, the NBA is in good hands. The league’s youngest stars aren’t just laying the groundwork for the future–they’re already dominating the present. Players early in their careers–many of whom have been YouTube-famous since they were in middle school–are leading their teams to playoff contention, redefining positions, and showing incredible athleticism, skill, and versatility.
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Jan 14, 2025 | 
complex.com | Aaron Mansfield
Despite all the complaints about the state of the league this season, the NBA is in good hands. The league’s youngest stars aren’t just laying the groundwork for the future–they’re already dominating the present. Players early in their careers–many of whom have been YouTube-famous since they were in middle school–are leading their teams to playoff contention, redefining positions, and showing incredible athleticism, skill, and versatility.
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Jan 8, 2025 | 
yahoo.com | Aaron Mansfield
There aren’t many players in the modern NBA who embody old-school toughness quite like Jimmy Butler. The Marquette product is relentless on defense, thrives in high-pressure situations, and demands the absolute best from his teammates. Since arriving in Miami in 2019, Butler has been the heart and soul of a Heat team that has consistently punched above its weight. But as much as his peers and NBA fans respect Butler’s grit, the reality is that he hasn’t won a ring.
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Jan 8, 2025 | 
complex.com | Aaron Mansfield
There aren’t many players in the modern NBA who embody old-school toughness quite like Jimmy Butler. The Marquette product is relentless on defense, thrives in high-pressure situations, and demands the absolute best from his teammates. Since arriving in Miami in 2019, Butler has been the heart and soul of a Heat team that has consistently punched above its weight. But as much as his peers and NBA fans respect Butler’s grit, the reality is that he hasn’t won a ring.
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Jan 7, 2025 | 
yahoo.com | Aaron Mansfield
The 2024 NFL regular season has been a rollercoaster of chaos, dominant quarterback play, and straight-up head-scratchers. Teams like the Jets and Cowboys–flush with preseason attention–proved to be all hype, quickly flaming out. Meanwhile, other teams far surpassed expectations (we’re looking at you, Vikings and Bills), but everyone is still chasing Patrick Mahomes and the Kansas City Chiefs, who somehow found a way to win week in and week out.
