Abraham J. Wu

Mar 12, 2023 | redjournal.org | Marsha Reyngold |Sana D. Karam |Carla Hajj |Abraham J. Wu

Purpose The optimal dose and fractionation of stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) have not been defined. Single-fraction SBRT was associated with more gastrointestinal toxicity, so 5-fraction regimens have become more commonly employed. We aimed to determine the safety and maximally tolerated dose of 3-fraction SBRT for LAPC.