Ainan Geng

Dec 19, 2023 | nature.com | Ainan Geng |Rohit Roy |Honglue Shi

AbstractSparse and short-lived excited RNA conformational states are essential players in cell physiology, disease, and therapeutic development, yet determining their 3D structures remains challenging. Combining mutagenesis, NMR spectroscopy, and computational modeling, we determined the 3D structural ensemble formed by a short-lived (lifetime ~2.1 ms) lowly-populated (~0.4%) conformational state in HIV-1 TAR RNA.

May 4, 2023 | dx.doi.org | Rohit Roy |Honglue Shi |Dawn K. Merriman |Ainan Geng

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May 4, 2023 | pubs.acs.org | Rohit Roy |Ainan Geng |Honglue Shi |Dawn K. Merriman

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).