Alan Moses

1 month ago | biorxiv.org | Alan Moses |Jason E. Stajich |Audrey P. Gasch |David Knowles

AbstractGene expression patterns are determined to a large extent by transcription factor binding to non-coding regulatory regions in the genome. However, gene expression cannot yet be systematically predicted from genome sequences, in part because non-functional matches to the sequence patterns (motifs) recognized by transcription factors (TFs) occur frequently throughout the genome.