Alan Zheng

London, Sydney

Freelance Journalist at Freelance

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Articles

Fast and flexible minimizer digestion with digest

Jan 8, 2025 | biorxiv.org | Alan Zheng |Ishmeal Lee |Vikram S. Shivakumar |Omar Ahmed

AbstractMinimizer digestion is an increasingly common component of bioinformatics tools, including tools for De Bruijn-Graph assembly and sequence classification. We describe a new open source tool and library to facilitate efficient digestion of genomic sequences. It can produce digests based on the related ideas of minimizers, modimizers or syncmers. Digest uses efficient data structures, scales well to many threads, and produces digests with expected spacings between digested elements.

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