Alasdair Leeson-Payne

Apr 24, 2024 | cell.com | Alasdair Leeson-Payne |Jean Iyinikkel |Cameron Malcolm |Brian Lam

Approximately 1 in 4 people worldwide have non-alcoholic fatty liver disease (NAFLD); however, there are currently no medications to treat this condition. This study investigated the role of adiposity-associated orphan G protein-coupled receptor 75 (GPR75) in liver lipid accumulation. We profiled Gpr75 expression and report that it is most abundant in the brain.