Alessia Pellerino

Jun 26, 2023 | mdpi.com | Riccardo Soffietti |Alessia Pellerino |Francesco Bruno |Alessandro Mauro

1. IntroductionImprovements in technology have allowed, in recent years, the delivery of more conformal doses of radiation to primary brain tumors in adults, for instance gliomas, thus minimizing the risk of late adverse effects in the normal brain. However, brain metastases or primary central nervous system lymphomas (PCNSL), due to their multiplicity, cannot profit from these conformal advances, and still need treatments covering a major part of the brain.