Alex G. Ortega-Loayza

May 8, 2024 | onlinelibrary.wiley.com | Divya Shan |NEHA GUPTA |Alex G. Ortega-Loayza |Sofia Shea

1 INTRODUCTION The hallmark feature of dermatomyositis (DM), an idiopathic inflammatory disorder, is symmetric proximal skeletal muscle weakness with characteristic cutaneous manifestations.1 Besides the pathognomonic findings of Gottron papules and heliotrope rash, other additional skin manifestations include facial erythema, shawl sign, poikiloderma, and calcinosis cutis.2 There can also be associated extramuscular manifestations, such as interstitial lung disease (ILD), myocarditis, and...

Feb 14, 2024 | jamanetwork.com | Hannah Zhao |Jonathan M. Sisley |Olivia Haddadin |Alex G. Ortega-Loayza

Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by painful skin ulcers commonly affecting the lower extremities.1 This rare condition’s pathophysiologic characteristics remain poorly understood.

Sep 20, 2023 | jamanetwork.com | Katherine M. Erickson |Shannon Kody |Alex G. Ortega-Loayza

Pain as a Patient-Reported Outcome Measure in Pyoderma Gangrenosum Pain is a major determinant of quality of life in patients with pyoderma gangrenosum, and pain relief may be an early sign of healing even before ulcer reepithelization.1 As a commonly and easily assessed symptom, pain is a candidate for a patient-reported outcome measure (PROM).

May 29, 2023 | dovepress.com | Sarah Becker |Rose Velasco |Alex G. Ortega-Loayza

IntroductionPyoderma gangrenosum (PG) is a rare, autoinflammatory disease which causes characteristic ulcerations with aseptic neutrophilic infiltration into the skin.