Alexander Liang

Dec 2, 2024 | aacrjournals.org | Caren Yu-Ju |Chang Gung |Alexander Liang |Ryan Takeo

Glioblastoma (GBM) is a highly aggressive brain tumor with poor prognosis and high recurrence rates. The complex immune microenvironment of GBM is highly infiltrated by tumor-associated microglia and macrophages (TAM). TAMs are known to be heterogeneous in their functional and metabolic states and can transmit either protumoral or antitumoral signals to glioma cells.