Alexander Lucas

Jun 1, 2023 | jacc.org | Alexander Lucas |Ralph B. D’Agostino |Jennifer Jordan |Kerryn Reding

Introduction Ascending (AAD) and descending (DAD) thoracic aorta distensibility, and thoracic aorta pulse wave velocity (PWV) reflect vascular stiffening that associates independently with subsequent cardiovascular (CV) events.1 Four to 6 months following cardiotoxic chemotherapy, AAD decreases and PWV increases.2,3 The goal of this prespecified secondary analysis of a previously published4 randomized trial, conducted in collaboration with the Wake Forest NCI Community Oncology Research...