Alexander Peikert

Apr 7, 2024 | jamanetwork.com | Alexander Peikert |Brian Claggett |Jacob A. Udell |Jacob Joseph

Key PointsQuestion  Does the antibody response to high-dose trivalent compared with standard-dose quadrivalent influenza vaccine differ among patients with recent myocardial infarction or hospitalization for heart failure, and are immune responses associated with adverse clinical outcomes?

Apr 1, 2024 | jacc.org | Alexander Peikert |Bradley A. Bart |Muthiah Vaduganathan |Brian Claggett

IntroductionBeta-blockers are cornerstone therapeutic agents for the management of heart failure with reduced ejection fraction (HFrEF). Conversely, high-quality randomized trial data on beta-blocker use among patients with heart failure with mildly reduced ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) remain sparse.

Mar 15, 2024 | onlinelibrary.wiley.com | Alexander Peikert |Muthiah Vaduganathan |Brian Claggett |Ian J. Kulac

Introduction Coronary artery disease is highly prevalent in patients with heart failure (HF).1, 2 Indeed, in many patients, myocardial ischaemia may represent a central driver of worsening HF and disease progression.

Jan 1, 2024 | jacc.org | Alexander Peikert |Muthiah Vaduganathan

References1. "Heart disease and stroke statistics-2023 update: a report from the American Heart Association". Circulation . 2023;147:e93-e621. 2. "Global Burden of Cardiovascular Diseases and Risks Collaborators. Global burden of cardiovascular diseases and risks, 1990-2022". J Am Coll Cardiol . 2023;82:25: 2350-2473. https://doi.org/10.1016/j.jacc.2023.11.007. 3. "Post-myocardial infarction heart failure". J Am Coll Cardiol HF . 2018;6:179-186. 4.

May 20, 2023 | jamanetwork.com | Alexander Peikert |Alvin Chandra |Mikhail Kosiborod |Brian Claggett

Association of Dapagliflozin vs Placebo With Individual Kansas City Cardiomyopathy Questionnaire Components in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Secondary Analysis of the DELIVER Trial Key Points Question What is the association between improvement in individual components of the Kansas City Cardiomyopathy Questionnaire (KCCQ) and treatment with dapagliflozin vs placebo in patients with heart failure with mildly reduced or preserved ejection...