Alexander Peikert

Apr 7, 2024 | jamanetwork.com | Alexander Peikert |Brian Claggett |Jacob A. Udell |Jacob Joseph

Key PointsQuestion  Does the antibody response to high-dose trivalent compared with standard-dose quadrivalent influenza vaccine differ among patients with recent myocardial infarction or hospitalization for heart failure, and are immune responses associated with adverse clinical outcomes?

Apr 1, 2024 | jacc.org | Alexander Peikert |Bradley A. Bart |Muthiah Vaduganathan |Brian Claggett

IntroductionBeta-blockers are cornerstone therapeutic agents for the management of heart failure with reduced ejection fraction (HFrEF). Conversely, high-quality randomized trial data on beta-blocker use among patients with heart failure with mildly reduced ejection fraction (HFmrEF) and heart failure with preserved ejection fraction (HFpEF) remain sparse.

Mar 15, 2024 | onlinelibrary.wiley.com | Alexander Peikert |Muthiah Vaduganathan |Brian Claggett |Ian J. Kulac

Introduction Coronary artery disease is highly prevalent in patients with heart failure (HF).1, 2 Indeed, in many patients, myocardial ischaemia may represent a central driver of worsening HF and disease progression.

Jan 1, 2024 | jacc.org | Alexander Peikert |Muthiah Vaduganathan

References1. "Heart disease and stroke statistics-2023 update: a report from the American Heart Association". Circulation . 2023;147:e93-e621. 2. "Global Burden of Cardiovascular Diseases and Risks Collaborators. Global burden of cardiovascular diseases and risks, 1990-2022". J Am Coll Cardiol . 2023;82:25: 2350-2473. https://doi.org/10.1016/j.jacc.2023.11.007. 3. "Post-myocardial infarction heart failure". J Am Coll Cardiol HF . 2018;6:179-186. 4.