Alexander V. Misharin

Jan 7, 2025 | nature.com | Connor H. Puritz |Karolina J. Senkow |Nikolay S. Markov |Estefani Diaz |Emmy Jonasson |Rogan A. Grant | +6 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-024-01975-x, published online 4 October 2024. In the version of this article initially published, there was a typographical error in the first paragraph of the Methods, where in the sentence now reading “Subsequent CT scans were obtained in 29 patients a median of 118 d (range 31–249 d) after the first CT scan,” the median was first reported as “11 d.” The error has been corrected in the HTML and PDF versions of the article.

Oct 4, 2024 | nature.com | Connor H. Puritz |Karolina J. Senkow |Nikolay S. Markov |Estefani Diaz |Emmy Jonasson |Rogan A. Grant | +6 more

AbstractMonocyte-derived alveolar macrophages drive lung injury and fibrosis in murine models and are associated with pulmonary fibrosis in humans. Monocyte-derived alveolar macrophages have been suggested to develop a phenotype that promotes lung repair as injury resolves.

Feb 2, 2023 | nature.com | Mohammad Lotfollahi |Alexander V. Misharin

AbstractThe increasing availability of large-scale single-cell atlases has enabled the detailed description of cell states. In parallel, advances in deep learning allow rapid analysis of newly generated query datasets by mapping them into reference atlases. However, existing data transformations learned to map query data are not easily explainable using biologically known concepts such as genes or pathways.