Alexandra Gerlach
Associate Editor at Pharmacy Times
Articles
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1 day ago |
pharmacytimes.com | Alexandra Gerlach
Researchers have identified p21-activated kinase 5 (PAK5) as a potential therapeutic target for overcoming trastuzumab emtansine (T-DM1, Kadcyla; Genentech) resistance in human epidermal growth factor receptor-positive (HER2+) breast cancer (BC), according to study findings published in Cell Death & Disease.1In 2023, approximately 290,000 women were diagnosed with HER2+ BC, which represents 20% of all BC diagnoses.
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2 days ago |
pharmacytimes.com | Alexandra Gerlach
Researchers have found associations between arterial and venous thrombosis and mortality, disease progression, cardiac events, and second cancers (SC) in myeloproliferative neoplasms (MPNs). The data, published in Blood Cancer Journal, suggest that common inflammatory pathways driving disease progression in MPNs could influence cardiovascular disease (CVD) and cancer incidence.1MPNs are clonal illnesses of the bone marrow and blood cells that are distinguished by aberrant hematopoietic growth.
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2 days ago |
pharmacytimes.com | Alexandra Gerlach
Cases of pertussis, also known as whooping cough, are on the rise alongside the ongoing measles outbreak as vaccination rates decline in children.
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3 days ago |
pharmacytimes.com | Alexandra Gerlach
Trastuzumab deruxtecan (T-DXd, Enhertu; AstraZeneca) in combination with pertuzumab (Perjeta; Genentech) demonstrated clinically meaningful improvement in progression-free survival (PFS) compared with a taxane, trastuzumab, and pertuzumab (THP) as a first-line treatment for patients with human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (mBC).
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6 days ago |
pharmacytimes.com | Alexandra Gerlach
As of April 18, 2025, the CDC has reported a total of 800 measles cases across the nation. Although the outbreak remains most concentrated in Texas, cases have now been confirmed in at least 12 states, as well as across the borders into Mexico and Canada. This represents a 12% increase from the prior week. The outbreak has led to 2 confirmed pediatric deaths and 1 case that is still under investigation.
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