Alexei Yavlinsky

Oct 19, 2024 | biorxiv.org | Cedric Tan |Marina Escalera-Zamudio |Alexei Yavlinsky |Lucy van Dorp

AbstractPredicting the fitness of mutations in the evolution of pathogens is a long-standing and important, yet largely unsolved problem. In this study, we used SARS-CoV-2 as a model system to explore whether the intrahost diversity of viral infections could provide clues on the relative fitness of single amino acid variants (SAVs).