Alexsandro dos Santos

Sep 22, 2024 | biorxiv.org | Sabine Elowe |Caroline DiOrio |Francine Durocher |Alexsandro dos Santos

AbstractErrors in mitosis can contribute to aneuploidy and CIN and play a pivotal role in cancer. So the identification of altered mitotic regulators can contribute to the understanding of the development and progression of breast cancer. In the present study we used an in vitro model of disease progression (the MCF10A series of BC continuum) and analyzed the errors of chromosome segregation that occur during the progression of the disease.