Alfredo Capretta

Apr 4, 2024 | chemistry-europe.onlinelibrary.wiley.com | Monsur Ali |Parameswaran Nair |Alfredo Capretta

Over the last three decades, significant advancements have been made in the development of biosensors and bioassays that use RNA-cleaving DNAzymes (RCDs) as molecular recognition elements. While early examples of RCDs were primarily responsive to metal ions, the past decade has seen numerous RCDs reported for more clinically relevant targets such as bacteria, cancer cells, small metabolites, and protein biomarkers.