Amadeus Plewnia

Mar 16, 2023 | science.org | Yue Zhai |Shaofan Yuan |Amadeus Plewnia |Philipp Böning

Information & AuthorsInformationPublished In ScienceVolume 379 | Issue 663717 March 2023CopyrightCopyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Article versionsSubmission historyPublished in print: 17 March 2023PermissionsRequest permissions for this article.

Mar 16, 2023 | science.org | Yue Zhai |Shaofan Yuan |Amadeus Plewnia |David Baltimore

Paul Berg, the pioneering biochemist who invented recombinant DNA technology, died on 15 February at age 96. Paul, whose work made genetic engineering possible, was a bridge between the traditional world of biochemistry and metabolism and the modern world of molecular biology. Born in Brooklyn, New York, on 30 June 1926, Paul served in the navy during World War II and then received a bachelor’s in biochemistry from Penn State University in 1948.

Mar 16, 2023 | science.org | Yue Zhai |Shaofan Yuan |Amadeus Plewnia |Chao Ma

Enhancing optical sensing and imagingOptical sensing and imaging can be considered as an encoding/decoding process in which the encoder is the hardware or device that takes the light signal or some property thereof (e.g., intensity, polarization, or spectral composition) and transduces that signal into usable information. The decoder is the software that then takes the information and converts it into something useful for the user. Yuan et al.

Mar 16, 2023 | science.org | Yue Zhai |Shaofan Yuan |Amadeus Plewnia |Brooke Williams

Australia recently declared the koala (Phascolarctos cinereus) an endangered species in Queensland, the Australian Capital Territory, and New South Wales (NSW) because of its stark population decline (1, 2). In the state of NSW, koala conservation has become a key topic of discussion in the lead-up to the 25 March state election (3). However, the debate has focused on the expansion of protected areas and overlooked the importance of private land conservation and regulation.

Mar 16, 2023 | science.org | Yue Zhai |Shaofan Yuan |Amadeus Plewnia |Liang Chen

Nabbing a neoantigenAutoimmunity can be caused by neoantigens that break immune tolerance. Zhai et al. profiled protein posttranslational modifications in patients with ankylosing spondylitis, an autoimmune disease (see the Perspective by Santambrogio). They found that that a cysteine residue of integrin αIIb was carboxyethylated in a process that required the gut microbe metabolite 3-hydroxypropionic acid (3-HPA) and resulted in pathogenic neoantigens.