Amanda Lund

Apr 10, 2024 | nature.com | Amanda Lund

AbstractLymphatic transport maintains homeostatic health and is necessary for immune surveillance, and yet lymphatic growth is often associated with solid tumour development and dissemination. Although tumour-associated lymphatic remodelling and growth were initially presumed to simply expand a passive route for regional metastasis, emerging research puts lymphatic vessels and their active transport at the interface of metastasis, tumour-associated inflammation and systemic immune surveillance.

Jul 6, 2023 | rupress.org | Amanda Lund

Lymph node metastasis in breast cancer depends in part on the acquisition of an IFN-dependent, MHC-II+ state that induces regulatory T cell expansion and local immune suppression (Lei et al. 2023. J. Exp. Med.https://doi.org/10.1084/jem.20221847). A new study by Lei et al. (2023) reveals a dynamic interplay between breast cancer cells and the lymph node (LN) microenvironment that sets up local immune suppression.

Mar 7, 2023 | bdo.no | Amanda Lund

Apr 14, 2022 | nursingsimulation.org | Amanda Lund