Amber M. Ridgway

Oct 21, 2024 | biorxiv.org | Amber M. Ridgway |Javier Jimenez |Javier Jiménez |Alistair P. McGregor |Oxford Brookes

AbstractDrosophila genitalia and legs are considered to be serially homologous appendages derived from a ventral appendage 'ground state' shaped by different Hox inputs. Despite their shared origin, there has been relatively little comparison between the downstream gene regulatory networks and how they may differently pattern and shape these appendages.

Feb 2, 2024 | cell.com | Amber M. Ridgway |Oxford Brookes |Emily Hood |Javier Jimenez

Highlights•Sox21b regulates development of posterior lobes, novel Drosophila genital organs•Higher Sox21b expression in developing genitalia produces smaller posterior lobes•Sox21b underlies posterior lobe divergence between D. simulans and D. mauritiana•The species allele of Sox21b causes differences in the duration of copulationSummary1York J.R. McCauley D.W. The origin and evolution of vertebrate neural crest cells. Open Biol.

Aug 18, 2023 | biorxiv.org | Emily Hood |Javier Jimenez |Alistair P. McGregor |Amber M. Ridgway

AbstractThe emergence and subsequent diversification of morphological novelties is a major feature of animal evolution1–9. However, in most cases little is known about the molecular basis of the evolution of novel structures and the genetic mechanisms underlying their diversification. The epandrial posterior lobes of the male genital arch is a novelty of some species of the Drosophila melanogaster subgroup10–13.