Andre Mu

Sep 5, 2024 | nature.com | Yan Shao |Andre Mu |Hilary P. Browne

AbstractHuman microbiota assembly commences at birth, seeded by both maternal and environmental microorganisms. Ecological theory postulates that primary colonizers dictate microbial community assembly outcomes, yet such microbial priority effects in the human gut remain underexplored. Here using longitudinal faecal metagenomics, we characterized neonatal microbiota assembly for a cohort of 1,288 neonates from the UK.

Feb 17, 2023 | nature.com | Andre Mu |Trevor D. Lawley

This Genome Watch explores how large-scale microbiome studies are facilitating discoveries in bacteriophage biology and functional capabilities that are prime for translation towards advances in biotechnology and biotherapeutics. Work by Adler et al.2 describes a 2-step in vitro technique for efficient genome editing of phages involving the broad-spectrum bacterial CRISPR–Cas13a.