Andreas Linkermann

Oct 22, 2024 | fis.tu-dresden.de | Ladan Golestaneh |Albert Einstein College |Abby Basalely |Andreas Linkermann

RATIONALE & OBJECTIVE: Animal models of kidney disease suggest a protective role for female sex hormones but in humans, some authorities assert that female sex is a risk factor for acute kidney injury (AKI). To better understand the risk of AKI, we studied the strength of association between sex and AKI incidence in hormonally distinct age groups across the life span. STUDY DESIGN: Prospective cohort study.

Mar 20, 2024 | nature.com | Andreas Linkermann

In two recent manuscripts published in Nature, the cholesterol-synthesis pathway was identified as a master regulator of ferroptosis sensitivity and therefore as a novel therapeutic target.1,2 Ferroptosis does not only represent one way to eliminate cancer cells, but also contributes to acute organ damage in the kidney, heart, brain, and liver, and it kills tissues during the process of organ transplantation.