Andrew Campbell

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Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model

Oct 24, 2024 | biorxiv.org | Ethan A. Older |Mary Mitchell |Andrew Campbell |Xiaoying Lian

AbstractCorrelative studies have linked human gut microbes to specific health conditions. Alistipes is one such microbial genus negatively linked to inflammatory bowel disease (IBD). However, the protective role of Alistipes in IBD has not been studied and the underlying molecular mechanisms also remain unknown. In this study, colonization of Il10-deficient mice with Alistipes timonensis DSM 27924 delays the development of colitis.

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