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Jan 13, 2025 | 
obgyn.onlinelibrary.wiley.com | Caroline S. Fox |Andrew H Shennan
Recently, the international company Hologic has withdrawn fetal fibronectin (fFN), a commonly used biomarker for preterm birth prediction. This is related to quality controls and sourcing consumables. However, fFN is currently recommended by the National Institute for Health and Care Excellence (NICE) and the National Health Service in England and had been implemented widely across Europe and the United Kingdom.
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Dec 12, 2024 | 
journals.plos.org | Andrew H Shennan
The rate of cesarean section has been increasing globally over several decades. Between 1990 and 2014, there was an absolute increase in cesarean section rate of 12.4%, translating to 1 in 5 women delivering by cesarean section worldwide [1]. In England, over 1 in 3 women deliver by cesarean section, and 24% of all deliveries are by emergency cesarean section, of which 5% are performed on women at full cervical dilatation [2,3].
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Sep 24, 2024 | 00527-x/fulltext?rss=yes&sz=64)
ejog.org | Lea Kirstine Hansen |Andrew H Shennan |Graham Tydeman
AbbreviationsPTB (Preterm birth)CT (Computed tomography)SD (Standard deviation)CI (Confidence interval)KeywordsCervical cerclageSimulation trainingPremature birthTransvaginal cerclageIntroductionA cervical cerclage is a mechanical support to the incompetent cervix to prevent mid-trimester loss or preterm birth (PTB) [1]. Live training for the procedure is challenging both due to low number of cases, and the procedure itself can be difficult due to poor visualization of the operative field [2–4].
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Feb 22, 2024 | 
allafrica.com | Andrew H Shennan |Megan Hall
Worldwide in 2020 a baby died every 40 seconds because of complications of prematurity. Preterm birth is the leading cause of death among children under 5 years old. The burden of preterm birth is heavier in in low- and middle-income countries, where around 80% occur. The countries with the highest recorded preterm rates in Africa are Malawi, South Africa, Ethiopia, the Democratic Republic of Congo and Botswana. In Ethiopia 12.9% of babies were born preterm in 2020. In Nigeria the figure was 9.9%.
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Feb 21, 2024 | 
theconversation.com | Andrew H Shennan |Megan Hall
Worldwide in 2020 a baby died every 40 seconds because of complications of prematurity. Preterm birth is the leading cause of death among children under 5 years old. The burden of preterm birth is heavier in in low- and middle-income countries, where around 80% occur. The countries with the highest recorded preterm rates in Africa are Malawi, South Africa, Ethiopia, the Democratic Republic of Congo and Botswana. In Ethiopia 12.9% of babies were born preterm in 2020. In Nigeria the figure was 9.9%.
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Feb 10, 2024 | 00068-x/abstract&sz=64)
ejog.org | Megan Preston |Megan Hall |Andrew H Shennan
Table 1A table summarising the predictive values of serum biomarkers: PAPP-A, PlGF, Beta-HCG, AFP, and Inhibin A in the prediction of spontaneous preterm birth and placental abruption. Serum BiomarkerValue in the prediction of spontaneous preterm birthValue in the prediction of placental abruptionPAPP-A•Association with preterm birth before 37 weeks gestation, especially when first trimester values are below the 1st centile.
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Dec 19, 2023 | 00859-x/abstract&sz=64)
ejog.org | Jana Hutter |Alena Uus |Carla L. Avena-Zampieri |Maria Deprez |Kelly Payette |Megan Hall | +7 more
Highlights•An MRI based approach and application of deformable slice-to-volume reconstruction is feasible for characterisation of preterm lung development. •Mean T2* values were lower in the preterm cohort than in controls. •Alterations in pulmonary development associated with preterm birth may commence in the antenatal period.
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Nov 20, 2023 | 
kcl.ac.uk | Andrew H Shennan |Josip Car
Professor Shennan takes over from Professor Lucilla Poston CBE, who has held the role since it was created in 1995Announced on World Prematurity Day (November 17), leading premature birth specialist and long-standing Tommy’s researcher Professor Andrew Shennan OBE has been appointed as Tommy’s Chair of Maternal and Fetal Health at King’s College London. Professor Shennan takes over from Professor Lucilla Poston CBE, who has held the role since it was created in 1995.
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Nov 18, 2023 | 00828-x/abstract&sz=64)
ejog.org | Megan Hall |Lindsay Wu |Andrew H Shennan
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Nov 8, 2023 | 
obgyn.onlinelibrary.wiley.com | Pedro Melo |Adam J. Devall |Andrew H Shennan |Manu Vatish
1 INTRODUCTION Hypertensive disorders of pregnancy (HDP), including gestational hypertension and pre-eclampsia, affect an estimated 18 million pregnant women worldwide every year.1 Women with HDP in previous pregnancies have an increased risk of spontaneous preterm birth2 and, conversely, women with spontaneous preterm births in previous pregnancies have an increased risk of HDP.3 The overlap in the groups of women who have these outcomes suggests common aetiological pathways, which could...
