Anette Breindl

Albany

Senior Science Editor at BioWorld

Managing Editor at BioWorld Science

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Articles

At EHA 2025, ways to bring immune therapy to AML

1 week ago | bioworld.com | Anette Breindl

At EHA 2025, ways to bring immune therapy to AML“The lack of therapeutic precision in treatment of myeloid malignancies is in sharp contrast with the fact that myeloid cancers represent the perhaps best characterized cancers of all at the cellular, molecular, and genetic levels,” Johanna Olweus told her audience at the Friday plenary session of the European Hematology Association 2025 Annual Congress. BioWorld Science Conferences European Hematology Association Cancer Hematologic
At EHA 2025, ways to bring immune therapy to AML

2 weeks ago | bioworld.com | Anette Breindl

At EHA 2025, ways to bring immune therapy to AML“The lack of therapeutic precision in treatment of myeloid malignancies is in sharp contrast with the fact that myeloid cancers represent the perhaps best characterized cancers of all at the cellular, molecular, and genetic levels,” Johanna Olweus told her audience at the Friday plenary session of the European Hematology Association 2025 Annual Congress. BioWorld Conferences European Hematology Association Cancer Hematologic
Insights into ‘intrinsic capacity’ could aid antiaging drug discovery

2 weeks ago | bioworld.com | Anette Breindl

AgingInsights into ‘intrinsic capacity’ could aid antiaging drug discoveryResearchers at the Buck Institute for Research on Aging have developed an epigenetic clock that could predict an individual’s intrinsic capacity score, a composite score that is a measure of healthy aging. The clock, which has only limited overlap with other epigenetic clocks, could be “a surrogate for aging that can be used for clinical trials,” senior author David Furman told BioWorld.
Open-source AI model can predict small-molecule binding affinity

2 weeks ago | bioworld.com | Anette Breindl

Drug design, drug delivery & technologiesOpen-source AI model can predict small-molecule binding affinityResearchers at the Massachusetts Institute of Technology and Recursion Pharmaceuticals Inc. have released an open-source AI model that can predict the binding strength of small molecules as well as structures of proteins and biomolecular complexes.
Open-source AI model can predict small-molecule binding affinity

2 weeks ago | bioworld.com | Anette Breindl

Open-source AI model can predict small-molecule binding affinityResearchers at the Massachusetts Institute of Technology and Recursion Pharmaceuticals Inc. have released an open-source AI model that can predict the binding strength of small molecules as well as structures of proteins and biomolecular complexes.
Precision medicine approach identifies culprit in alcohol-associated hepatitis

1 month ago | bioworld.com | Anette Breindl

Home » Precision medicine approach identifies culprit in alcohol-associated hepatitisGastrointestinalPrecision medicine approach identifies culprit in alcohol-associated hepatitisResearchers have identified KpsM as a virulence factor in Escherichia coli that was responsible for liver damage in alcohol-associated hepatitis (AH). A small-molecule inhibitor of KpsM reduced liver damage in animal models of AH. BioWorld Science Gastrointestinal Immune
Study probes link between sickle cell disease and kidney cancer

1 month ago | bioworld.com | Anette Breindl

Individuals with both sickle cell disease (SCD) and sickle cell trait are at higher risk than others of developing renal medullary cancer (RMC), the rarest and deadliest subtype of kidney cancer. Researchers at MD Anderson Cancer Center have identified the molecular mechanisms behind the increased risk, gaining new insights into antitumor immunity more generally and, potentially, new ways to treat RMC, and possibly other tumors as well.
First bespoke gene editing therapy treats rare metabolic disease

1 month ago | bioworld.com | Anette Breindl

ASGCT 2025First bespoke gene editing therapy treats rare metabolic diseaseUsing a customized gene editing therapy, researchers at the Children’s Hospital of Philadelphia have reported success in treating an infant with a severe metabolic disorder. Kiran Musunuru, Barry J. Gertz Professor for Translational Research in the University of Pennsylvania’s Perelman School of Medicine, presented the case at the American Society of Gene and Cell Therapy’s 2025 annual meeting.
First bespoke gene editing therapy treats rare metabolic disease

1 month ago | bioworld.com | Anette Breindl

ASGCT 2025First bespoke gene editing therapy treats rare metabolic diseaseUsing a customized gene editing therapy, researchers at the Children’s Hospital of Philadelphia have reported success in treating an infant with a severe metabolic disorder. Kiran Musunuru, Barry J. Gertz Professor for Translational Research in the University of Pennsylvania’s Perelman School of Medicine, presented the case at the American Society of Gene and Cell Therapy’s 2025 annual meeting.
Liver is also immune organ, influenced by microbiome

1 month ago | bioworld.com | Anette Breindl

Endocrine/metabolicLiver is also immune organ, influenced by microbiomeImmunity is not a function most people particularly associate with the liver. But because of its connection to the gut, the liver is exposed to bacterial metabolites as few other organs are. And when either the liver or the gut is not functioning well, it can adversely affect immunity as well. BioWorld MedTech Science Conferences Microbiome Endocrine/metabolic Gastrointestinal Immune