Angelita Liang

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Alternative splicing in 300 human cells and tissues is sparsely distributed and strongly associated with cell identity

Jan 6, 2025 | biorxiv.org | Marc Wilkins |Angelita Liang

AbstractIn eukaryotes, alternative splicing allows RNA sequences to be changed as required in their cellular context. While the use of gene expression without considering transcript isoforms is commonly used to classify cell types, the significance of alternative splicing to cell identity is not fully understood.

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