Anindya Ganguly

Jul 16, 2024 | cell.com | Nicole Leung |Chiwei Xu |Anindya Ganguly |Geoff T. Meyerhof

In this work, Leung et al. demonstrate that fruit flies with gut tumors display an increased propensity to consume the normally aversive anti-tumorigenic compound aristolochic acid. The change in taste valence for aristolochic acid may be a form of self-medication as feeding on aristolochic acid suppressed the gut tumors.

May 31, 2024 | cell.com | Nicole Leung |Chiwei Xu |Anindya Ganguly

Highlights•Gut tumors cause flies to increase their ingestion of anti-tumorigenic compounds•Gut tumors do not affect avoidance of aversive compounds devoid of anti-tumor effects•Increased consumption of anti-tumorigenic compounds suppresses gut tumors•Shift in taste valence due to tumors occurs via a mechanism postsynaptic to taste neuronsSummaryThe sense of taste is essential for survival, as it allows animals to distinguish between foods that are nutritious from those that are toxic.

May 19, 2023 | pubmed.ncbi.nlm.nih.gov | Manali Dey |Anindya Ganguly |Anupama Dahanukar

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