Anna K. Orta

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Articles

RHINO directs MMEJ to repair DNA breaks in mitosis

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |Alessandra Brambati

AbstractNon-homologous end-joining (NHEJ) and homologous recombination (HR) are the primary pathways for repairing DNA double-strand breaks (DSBs) during interphase, while microhomology-mediated end-joining (MMEJ) has been regarded as a backup mechanism. Through CRISPR/Cas9-based synthetic lethal screens, we identify subunits of the 9-1-1 complex (RAD9A-HUS1-RAD1) and its interacting partner, RHINO, as crucial MMEJ factors.
Undue publicity for flawed fraud detector

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |Carl T Bergstrom

(0)eLetters eLetters is a forum for ongoing peer review. eLetters are not edited, proofread, or indexed, but they are screened. eLetters should provide substantive and scholarly commentary on the article. Embedded figures cannot be submitted, and we discourage the use of figures within eLetters in general. If a figure is essential, please include a link to the figure within the text of the eLetter. Please read our Terms of Service before submitting an eLetter. Log In to Submit a Response
Erratum for the Research Article “Garnet crystallization does not drive oxidation at arcs” by M. Holycross and E. Cottrell

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang

Science 14 July 2023Vol. 381, Issue 6654, eadj6418DOI: 10.1126/science.adj6418 SIGN UP FOR THE SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Correction to Holycross et al., Science380, 506 (2023)Erratum for the Research Article “Garnet crystallization does not drive oxidation at arcs” by M. Holycross and E.
New Products

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang

Ultra-Low Adherence Cell Culture PlateSARSTEDT introduces the BIOFLOAT 96-well Ultra-Low Adherence cell culture plate specifically for culturing spheroids. The BIOFLOAT surface is anti-adhesive, which repels cells of all types, preventing them from attaching to the surface of the plate. This, along with the round bottoms of the wells, results in cells growing into 3D spheroids.
Implications of predicting race variables from medical images

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |James Zou

(0)eLetters eLetters is a forum for ongoing peer review. eLetters are not edited, proofread, or indexed, but they are screened. eLetters should provide substantive and scholarly commentary on the article. Embedded figures cannot be submitted, and we discourage the use of figures within eLetters in general. If a figure is essential, please include a link to the figure within the text of the eLetter. Please read our Terms of Service before submitting an eLetter. Log In to Submit a Response
In Other Journals

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |Di Jiang

Evolution A hearty eaterDi JiangMany plant-eating insects are picky eaters and specialize on a single host plant. Some species do have generalist appetites, but whether they use the same biochemical processes as specialists to convert different foods into energy and other bioactive molecules is not well understood. Olazcuaga et al.
Engineering ligand reactivity enables high-temperature operation of stable perovskite solar cells

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |Mingyang Wei

Editor’s summaryThe thermal stability of three-dimensional perovskite solar cells can be improved by adding ammonium ligands that create a two-dimensional perovskite capping layers, but such ligands are prone to intercalation into the bulk. Park et al.
Multichip multidimensional quantum networks with entanglement retrievability

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |Yun Zheng

Information & AuthorsInformationPublished In ScienceVolume 381 | Issue 665414 July 2023CopyrightCopyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. This is an article distributed under the terms of the Science Journals Default License.
The central role of density functional theory in the AI age

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang

AbstractDensity functional theory (DFT) plays a pivotal role in chemical and materials science because of its relatively high predictive power, applicability, versatility, and computational efficiency. We review recent progress in machine learning (ML) model developments, which have relied heavily on DFT for synthetic data generation and for the design of model architectures. The general relevance of these developments is placed in a broader context for chemical and materials sciences.
Biasing the quantum vacuum to control macroscopic probability distributions

Jul 13, 2023 | science.org | Fei Huang |Anna K. Orta |Bing Huang |Charles Roques-Carmes

Editor’s summaryThe state of quantum mechanical systems fluctuates. In optics, these fluctuations can be harnessed for the generation of truly random bit strings. The random fluctuations can also be used in probabilistic computing, but this requires the probability distributions to be controllable. Using the two-state phase output from an optical parametric amplifier as a “bit, ” Roques-Carmes et al.