Anthony Jeffrey

Jul 31, 2023 | onlinelibrary.wiley.com | George Mason |Ian Kerridge |Anthony Jeffrey |Poomahal Kumar

A 30 year old female presented with a 4 month history of an enlarging right posterior thigh mass. Biopsy of the lesion demonstrated an angioinvasive atypical lymphoid infiltrate with pleomorphic nuclei and prominent nucleoli. The immunohistochemical profile was consistent with a diagnosis of extranodal NK/T cell lymphoma: atypical lymphoid cells were positive for CD2, CD3, CD7, CD45RO, CD30, CD8 and cytotoxic molecules (Granzyme B, TIA1, Perforin). CD5 was lost in most cells.