Anton Gisterå

Mar 10, 2024 | nature.com | Yuyang Zhang |Osman Ahmed |Linn Fagerberg |Anton Gisterå |Carolina E. Hagberg |Peder S. Olofsson | +1 more

AbstractApolipoprotein-B (APOB)-containing lipoproteins cause atherosclerosis. Whether the vasculature is the initially responding site or if atherogenic dyslipidemia affects other organs simultaneously is unknown. Here we show that the liver responds to a dyslipidemic insult based on inducible models of familial hypercholesterolemia and APOB tracing.