Antonis Rokas

Jan 9, 2024 | biorxiv.org | Alec Brown |Jacob L. Steenwyk |Antonis Rokas

AbstractA. fumigatus is a deadly fungal pathogen, responsible for >400,000 infections/year and high mortality rates. A. fumigatus strains exhibit variation in infection-relevant traits, including in their virulence. However, most A. fumigatus protein-coding genes, including those that modulate its virulence, are shared between A. fumigatus strains and closely related non-pathogenic relatives. We hypothesized that A.

Oct 19, 2023 | journals.plos.org | Jacob L. Steenwyk |Antonis Rokas |Gustavo H. Goldman |PLOS Pathogens

Loading metrics Open Access Pearls Pearls provide concise, practical and educational insights into topics that span the pathogens field. See all article types » Citation: Steenwyk JL, Rokas A, Goldman GH (2023) Know the enemy and know yourself: Addressing cryptic fungal pathogens of humans and beyond. PLoS Pathog 19(10): e1011704.

Sep 12, 2023 | biorxiv.org | Allison S. Walker |Antonis Rokas |Olivia Riedling

AbstractFungal secondary metabolites (SMs) play a significant role in the diversity of ecological communities, niches, and lifestyles in the fungal kingdom. Many fungal SMs have medically and industrially important properties including antifungal, antibacterial, and antitumor activity, and a single metabolite can display multiple types of bioactivities. The genes necessary for fungal SM biosynthesis are typically found in a single genomic region forming biosynthetic gene clusters (BGCs).

Sep 8, 2023 | sfgate.com | Antonis Rokas

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.)(THE CONVERSATION) By the end of every spring semester, students in my introductory biology course at Vanderbilt University have become quite familiar with natural variation in human sex chromosomes. They know, for example, that most females have two X chromosomes and most males have one X and one Y chromosome.

Sep 8, 2023 | houstonchronicle.com | Antonis Rokas

Most Popular (The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Antonis Rokas, Vanderbilt University (THE CONVERSATION) By the end of every spring semester, students in my introductory biology course at Vanderbilt University have become quite familiar with natural variation in human sex chromosomes.