Aoba-ku Sendai Japan

Mar 1, 2024 | onlinelibrary.wiley.com | Kanako Teramoto |Kotaro Nochioka |Aoba-ku Sendai Japan |Yasuhiko Sakata

Introduction Growth differentiation factor-15 (GDF15) is a member of the transforming growth factor beta superfamily known to be up-regulated in response to oxidative stress, tissue injury, and subsequent inflammation.1 Previous studies suggested robust associations between GDF15 and a variety of diseases, including heart failure (HF), cancer, cognitive decline, pulmonary diseases, diabetes, and renal disease.2-6 Its remarkable cardioprotective properties7 and prognostic significance in...