Ariana Gatt

Jun 15, 2023 | mdpi.com | Ariana Gatt |Tammaryn Lashley |Xinwa Jiang

Abstract:Frontotemporal dementia (FTD) is the second most common form of young-onset (<65 years) dementia. Clinically, it primarily manifests as a disorder of behavioural, executive, and/or language functions. Pathologically, frontotemporal lobar degeneration (FTLD) is the predominant cause of FTD. FTLD is a proteinopathy, and the main pathological proteins identified so far are tau, TAR DNA-binding protein 43 (TDP-43), and fused in sarcoma (FUS).

Mar 1, 2023 | mdpi.com | Ariana Gatt |Tammaryn Lashley |Rina Bandopadhyay

Open AccessEditorialbyRina Bandopadhyay 1,*, Ariana Gatt 2 and Tammaryn Lashley 2 1Reta Lila Weston Institute of Neurological Studies, Department of Clinical and Movement Neuroscience, UCL Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK2Queen Square Brain Bank, Department of Neurodegenerative Diseases, UCL Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK*Author to whom correspondence should be addressed.