Ariane Delgado-Sanchez

Oct 16, 2024 | biorxiv.org | Nicola Ray |Natalia Cullell |Oliver Clark |Ariane Delgado-Sanchez

AbstractBACKGROUND: The glymphatic system is thought to facilitate waste clearance from the brain during sleep. Impairment in this system may underpin the elevated deposition of pathological proteins in neurodegenerative conditions like Alzheimer's disease (AD). Putative glymphatic system activity has been measured with contrast-enhanced, serial MRI, revealing slower clearance in people who are sleep deprived.