Ashley M. Frank

Dec 8, 2023 | biorxiv.org | Ashley M. Frank |William Pearson |Destiny O. Okoro |Sophia N. Aredas

AbstractOvernutrition with dietary sugar can worsen infection outcomes in diverse organisms including insects and humans, generally through unknown mechanisms. In the present study, we show that adult Drosophila melanogaster fed high-sugar diets became more susceptible to infection by the Gram-negative bacteria Providencia rettgeri and Serratia marcescens, although diet had no significant effect on infection by Gram-positive bacteria Enterococcus faecalis or Lactococcus lactis. We found that P.