Ayazoddin Aunoddin Kazi

Jul 25, 2024 | pubs.rsc.org | L Singh |Ayazoddin Aunoddin Kazi

A quick access to CF3-containing functionalized benzofuranyl, benzothiophene and indolyl heterocycles under catalyst-free conditions A catalyst-free one pot synthetic protocol is presented for the preparation of CF3 containing benzofuran, indolin, benzothiophene derivative using readily available aromatic aldehydes and ketones. 2-Bromo-3,3,3-trifluoropropene employed as a non-corrosive and environmentally benign trifluoromethylacetylene synthon for incorporation of CF3 group.