Ayyub Ebrahimi

3 weeks ago | biorxiv.org | Yang Cao |Oleksandr Dovgusha |Stephen Bevan |Ayyub Ebrahimi

AbstractEnhancers are key gene regulatory elements that ensure the precise spatiotemporal execution of developmental gene expression programmes. However recent findings indicate that approaches to identify enhancers may not capture the full repertoire of active enhancers in mammalian genomes. Here, we combine massively parallel enhancer assays with chromatin structure and transcriptome profiling to functionally annotate enhancers genome-wide in human induced pluripotent stem cells.