Balraj S. Sandhar

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Tissue-resident memory T cells in epicardial adipose tissue comprise transcriptionally distinct subsets that are modulated in atrial fibrillation - Nature Cardiovascular Research

Aug 22, 2024 | nature.com | Balraj S. Sandhar |Jack Keane |Hazel Blythe |Aled Jones |Silvia Fanti |Mirjana Efremova | +5 more

AbstractAtrial fibrillation (AF) is the most common sustained arrhythmia and carries an increased risk of stroke and heart failure. Here we investigated how the immune infiltrate of human epicardial adipose tissue (EAT), which directly overlies the myocardium, contributes to AF. Flow cytometry analysis revealed an enrichment of tissue-resident memory T (TRM) cells in patients with AF.

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