Articles

  • 2 weeks ago | fiercebiotech.com | Ben Adams

    Gilead has been hit with a clinical hold from the FDA for five tests of its experimental HIV combination treatment amid safety concerns. In a statement released Tuesday, June 10, the Californian Big Pharma said trials of GS-1720, an investigational integrase strand transfer inhibitor, and/or GS-4182, an investigational capsid inhibitor, had been put on a full FDA hold. The drugs had been in two phase 2/3 tests known as WONDERS-1 and WONDERS-2, as well as three earlier phase 1 studies.

  • 1 month ago | fiercebiotech.com | Ben Adams

    CRISPR Therapeutics is paying $25 million upfront to work on multiple siRNA targets with Sirius Tx with an early focus on the next-gen thrombotic disease asset SRSD107. That drug, Sirius’ lead program, works as a long-acting, next-generation anticoagulant for thromboembolic disorders that after passing early phase 1 tests is gearing up for midstage trials.

  • 1 month ago | fiercebiotech.com | Ben Adams

    GSK has already moved on from its decision to drop a cancer asset on Tuesday by snagging a late-stage liver disease candidate for a hefty $1.2 billion upfront. That drug in question is efimosfermin, Boston Pharmaceuticals’ lead asset. The asset has already passed midstage tests and is in now a phase 3-ready therapy to help stop the progression of steatotic liver disease (SLD), a condition where fat builds up in the liver.

  • 1 month ago | fiercebiotech.com | Ben Adams |Gabrielle Masson

    San Diego-based RNA biotech Arcturus is doubling down on mRNA therapeutics and stepping back from earlier-stage vaccine work in an effort to prioritize spending and extend its cash runway.

  • 1 month ago | fiercebiotech.com | Ben Adams

    Qilu Pharmaceutical is paying 280 million Chinese yuan ($38 million) for a licensing and collaboration deal with fellow China biopharma Minghui Pharmaceutical. The pact centers on MHB088C, a B7-H3-targeted antibody-drug conjugate that is in trials for solid tumors, including in subgroups of patients with small cell lung cancer and metastatic castration-resistant prostate cancer.

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BenAdamsFierce
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