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1 week ago | 
multiplesclerosisnewstoday.com | Margarida Maia |Benjamin Hofmeister |Marisa Wexler
Biostate AI is partnering with the nonprofit Accelerated Cure Project (ACP) to develop a series of artificial intelligence (AI) models that can predict multiple sclerosis (MS) progression and how patients may respond to treatment. As part of the partnership, Biostate AI will use its high-throughput technology to profile RNA reads from ACP’s large collection of MS patient samples. RNA reads can be used as a measure of how active different genes are.
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1 week ago | 
multiplesclerosisnewstoday.com | Margarida Maia |Lindsey Shapiro |Benjamin Hofmeister |Marisa Wexler
Frexalimab, an experimental antibody-based medication, was well tolerated and maintained disease control over two years in adults with relapsing forms of multiple sclerosis (MS). That’s according to new data from an open-label extension to a Phase 2 clinical trial (NCT04879628) in which frexalimab outperformed a placebo at reducing the number of active and new or enlarging brain lesions in adults with relapsing-remitting MS or active secondary progressive MS (SPMS) after 12 weeks.
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3 weeks ago | 
multiplesclerosisnewstoday.com | Marisa Wexler |Lindsey Shapiro |Benjamin Hofmeister
A small molecule that blocks the activity of a protein called TYK2 in the brain showed promise at reducing disease activity in mouse models of multiple sclerosis (MS), according to a study. The study was conducted by Neuron23, which is advancing a small molecule TYK2 inhibitor called NEU-627 to treat MS. That molecule is expected to enter early safety testing in healthy volunteers in the first half of this year.
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3 weeks ago | 
multiplesclerosisnewstoday.com | Ahna Crum |Marisa Wexler |Benjamin Hofmeister
Recently, my work-life balance felt off, so I took the opportunity to house-sit a family farm. I needed the solitude — the peace and quiet — to recharge. While there, I watched a flock of 50 to 60 goldfinches gather at the bird feeders daily. Their communal nature fascinated me, so I did a little reading on these bright yellow birds. Goldfinches, I learned, don’t defend a territory once they’ve started a family, which is unlike most birds.
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1 month ago | 
multiplesclerosisnewstoday.com | Lindsey Shapiro |Benjamin Hofmeister
Sarah Zichterman poses for a photo one year after her MS diagnosis. (Photos courtesy of Sarah Zichterman) Day 10 of 31This is Sarah Zichterman’s story:Getting diagnosed with MS was not something I thought would happen to me at age 24. One day in January 2024, I woke up and realized my vision felt a bit off, so I went to the emergency room to get checked out.
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1 month ago | 
multiplesclerosisnewstoday.com | Lindsey Shapiro |Benjamin Hofmeister
Naty Caez shares about her life with MS on Instagram. (Photos courtesy of Naty Caez) Day 9 of 31This is Naty Caez’s story:In September 2024, I was diagnosed with multiple sclerosis (MS). Everyone’s diagnosis story is going to look a little different, but for me, it took nearly six months of doctor’s visits and exams to get answers.
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1 month ago | 
multiplesclerosisnewstoday.com | Lindsey Shapiro |Benjamin Hofmeister
Amy Behimer sits in a rocking chair in her home. (Photos courtesy of Amy Behimer) Day 7 of 31This is Amy Behimer’s story:When I was first diagnosed with multiple sclerosis (MS), I thought my chance at a healthy, happy life was gone. As a pharmacist, the way I had always understood health — defined as the absence of symptoms or disease — meant that my officially chronic, progressive, neurodegenerative diagnosis would make it near impossible.
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1 month ago | 
multiplesclerosisnewstoday.com | Leigh Nelson |Patricia Inacio |Benjamin Hofmeister |Susan Payrovi
I’ve noticed a lot of people with multiple sclerosis (MS) report that their disease worsens in the summer months, with fatigue and heat intolerance as common complaints. Not me. I seem to thrive in warmer weather, and I enjoy going outside for the heat. Instead, I struggle in the winter, and this year’s winter in Kansas City, Missouri, has felt particularly rough. We usually have what we consider milder weather, but these past months have brought us “snowmageddon,” ice storms, and frigid cold.
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1 month ago | 
multiplesclerosisnewstoday.com | Benjamin Hofmeister |Lindsey Shapiro
From left, Michael Lee Martinez and Feliciano Velazquez celebrate the holiday with their cats, Korra and Cleo, on Dec. 23, 2024. (Photos courtesy of Michael Lee Martinez) Day 2 of 31This is Michael Lee Martinez’s story:Picture this: After stanning one of the biggest pop stars of our generation for the last 13 years, I’m less than 20 feet from Lady Gaga.
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1 month ago | 
multiplesclerosisnewstoday.com | Marisa Wexler |Benjamin Hofmeister
Sanam Saeedi resolved not to allow a diagnosis of MS to determine the course her life could take. (Photos courtesy of Sanam Saeedi) Day 1 of 31This is Sanam Saeedi’s story:For years, I lived with numbness and tingling in my toes, but dismissed it as a result of old skiing injuries. I never imagined that those subtle sensations would be the early signs of something far more serious.
