Bérénice A. Benayoun

Sep 11, 2024 | biorxiv.org | Juan Bravo |Lucia Zhang |Bérénice A. Benayoun

ABSTRACTLong INterspersed Element-1 (LINE-1; L1) and Alu are two families of transposable elements (TEs) occupying ∼17% and ∼11% of the human genome, respectively. Though only a small fraction of L1 copies is able to produce the machinery to mobilize autonomously, Alu elements and degenerate L1 copies can hijack their functional machinery and mobilize in trans.

Jun 29, 2023 | nature.com | Bérénice A. Benayoun

AbstractTechnical advancements over the past two decades have enabled the measurement of the panoply of molecules of cells and tissues including transcriptomes, epigenomes, metabolomes and proteomes at unprecedented resolution. Unbiased profiling of these molecular landscapes in the context of aging can reveal important details about mechanisms underlying age-related functional decline and age-related diseases.