Bernd Schnabl

3 weeks ago | jci.org | Bernd Schnabl |Christopher J. Damman |Rotonya M. Carr

AbstractMetabolic dysfunction–associated steatotic liver disease (MASLD) is a major cause of liver disease worldwide, and our understanding of its pathogenesis continues to evolve. MASLD progresses from steatosis to steatohepatitis, fibrosis, and cirrhosis, and this Review explores how the gut microbiome and their metabolites contribute to MASLD pathogenesis.