Bianca M. Leca

May 20, 2024 | thelancet.com | Bianca M. Leca |Warwickshire NHS Trust |Shahd Alabdulkader

SummaryPolycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Obesity exacerbates the reproductive complications of PCOS; however, the management of obesity in women with PCOS remains a large unmet clinical need.

Jun 23, 2023 | frontiersin.org | Harpal S Randeva |Thomas Barber |Bianca M. Leca

1 IntroductionPolycystic ovary syndrome (PCOS) is a common reproductive and endocrine disease affecting 6–10% of women of reproductive age worldwide (1). This syndrome is mostly characterized by menstrual disorder, infertility, abnormal increase in the level of androgen, and a polycystic ovary (2). Many PCOS patients have metabolic disorders, including insulin resistance, obesity, and abnormal lipid metabolism (3).