Bing Cai

Aug 16, 2024 | journals.plos.org | Catherine Byrne |Ana Marquez |Bing Cai |Daniel Coombs

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Byrne CM, Márquez AC, Cai B, Coombs D, Gantt S (2024) Spatial kinetics and immune control of murine cytomegalovirus infection in the salivary glands. PLoS Comput Biol 20(8): e1011940.

Feb 26, 2024 | biorxiv.org | Catherine Byrne |Ana Marquez |Bing Cai |Daniel Coombs

AbstractHuman cytomegalovirus (HCMV) is the most common congenital infection. Several HCMV vaccines are in development, but none have yet been approved. An understanding of the kinetics of CMV replication and transmission may inform the rational design of vaccines to prevent this infection. The salivary glands (SG) are an important site of sustained CMV replication following primary infection and during viral reactivation from latency.